Article
Role of reactive oxygen species in skin carcinogenesis.
Antioxidants & redox signaling - 1 Jun 2004
Nishigori Chikako, Hattori Yukari, Toyokuni Shinya
Abstract excerpt
Reactive oxygen species (ROS) are associated not only with initiation, but also with promotion and progression in the multistage carcinogenesis model. In the present review, we will focus on the involvement of ROS in skin carcinogenesis, especially that induced by ultraviolet (UV) radiation. UV-specific DNA damage has been well studied thus far. However, recent reports have revealed the previously unknown...
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