A CDE/CHR-like element mediates repression of transcription of the mouse RB2 (p130) gene.

doi:10.1016/s0014-5793(00)01363-6

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Article

A CDE/CHR-like element mediates repression of transcription of the mouse RB2 (p130) gene.

FEBS letters - 7 Apr 2000

Fajas L, Le Cam L, Polanowska J, Fabbrizio E, Servant N, Philips A, Carnac G, Sardet C

Abstract excerpt

The bipartite repressor elements, termed cell cycle-dependent element (CDE)/cell cycle regulatory element (CCRE)-cell cycle homology region (CHR) control the growth-dependent transcription of the cyclin A, cdc25C, cdc2 genes. Here, we have identified a functional element displaying the signature of the CDE-CHR in the promoter of the mouse RB2 (p130) gene, encoding the retinoblastoma protein family (pRB)-related...

Topics

Animals
Base Sequence
Cloning, Molecular
DNA
DNA-Binding Proteins
Gene Expression Regulation
Genes, cdc
Humans
Mice
Molecular Sequence Data
Mutation
Phosphoproteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Promoter Regions, Genetic

Proteins

Retinoblastoma-Like Protein p130

Sequence Homology, Nucleic Acid

Transcription, Genetic

Up-Regulation

Source

Open in PubMed

Identifiers

PMID: 10760507
DOI: 10.1016/s0014-5793(00)01363-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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