Article
Premature termination codons destabilize ferredoxin-1 mRNA when ferredoxin-1 is translated.
The Plant journal : for cell and molecular biology - 1 Mar 2000
Petracek M E, Nuygen T, Thompson W F, Dickey L F
Abstract excerpt
Ferredoxin-1 (Fed-1) mRNA is poorly translated in dark-treated tobacco (Nicotiana tabacum) leaves, resulting in destabilization of Fed-1 mRNA and a differential light/dark accumulation of the mRNA. Insertion of nonsense codons within the Fed-1 coding sequence disrupts the light regulation of Fed-1 mRNA abundance. Here we show that the nonsense codon effect results primarily from lowering the Fed-1 mRNA stability...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.