Article
Improved bacterial SOS promoter∷lux fusions for genotoxicity detection.
Mutation research - 3 Mar 2000
Davidov Y, Rozen R, Smulski D R, Van Dyk T K, Vollmer A C, Elsemore D A, LaRossa R A, Belkin S
Abstract excerpt
Escherichia coli strains containing plasmid-borne fusions of Vibrio fischeri lux to the recA promoter-operator region were previously shown to be potentially useful for detecting genotoxicants. In an attempt to improve past performance, the present study examines several modifications and variations of this design, singly or in various combinations: (1) modifying the host cell's toxicant efflux capacity via a...
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