Article
Asymmetric requirements for a Rab GTPase and SNARE proteins in fusion of COPII vesicles with acceptor membranes.
The Journal of cell biology - 3 Apr 2000
Cao X, Barlowe C
Abstract excerpt
Soluble NSF attachment protein receptor (SNARE) proteins are essential for membrane fusion in transport between the yeast ER and Golgi compartments. Subcellular fractionation experiments demonstrate that the ER/Golgi SNAREs Bos1p, Sec22p, Bet1p, Sed5p, and the Rab protein, Ypt1p, are distributed similarly but localize primarily with Golgi membranes. All of these SNARE proteins are efficiently packaged into COPII...
Topics
- Alleles
- Biological Transport
- Cell Membrane
- Cytoplasmic Granules
- Endoplasmic Reticulum
- Fungal Proteins
- Genes, Fungal
- Golgi Apparatus
- Intracellular Membranes
- Membrane Fusion
- Membrane Proteins
- Mutation
- Recombinant Fusion Proteins
- SNARE Proteins