Got1p and Sft2p: membrane proteins involved in traffic to the Golgi complex.

doi:10.1093/emboj/18.14.3934

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Article

Got1p and Sft2p: membrane proteins involved in traffic to the Golgi complex.

The EMBO journal - 15 Jul 1999

Conchon S, Cao X, Barlowe C, Pelham H R

Abstract excerpt

Traffic through the yeast Golgi complex depends on a member of the syntaxin family of SNARE proteins, Sed5p, present in early Golgi cisternae. Sft2p is a non-essential tetra-spanning membrane protein, found mostly in the late Golgi, that can suppress some sed5 alleles. We screened for mutations that show synthetic lethality with sft2 and found one that affects a previously uncharacterized membrane protein, Got1p,...

Topics

Alleles
Amino Acid Sequence
Animals
Biological Transport
COS Cells
Cloning, Molecular
Conserved Sequence
Endoplasmic Reticulum
Endosomes
Fungal Proteins
Genes, Fungal
Genes, Lethal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Complementation Test

Golgi Apparatus

Membrane Fusion

Membrane Proteins

Molecular Sequence Data

Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 10406798
DOI: 10.1093/emboj/18.14.3934
PMCID: PMC1171469

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-10406798-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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