Helicobacter pylori infection, host genetics and gastric cancer.

Abstract excerpt

Helicobacter pylori infects half the world's population and is responsible for a considerable global health burden, including peptic ulcer disease and gastric cancer. The infection causes a chronic gastritis, the severity and distribution of which determine the clinical outcome. Bacterial, environmental and host genetic factors combine to define the degree of gastric damage. Most patients have a limited mild...

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• Gastritis
• Helicobacter Infections
• Helicobacter pylori
• Interleukin-1
• Multigene Family
• Peptic Ulcer