Article
Activation of NF-kappa B in human endothelial cells induced by monoclonal and allospecific HLA antibodies.
International immunology - 1 Apr 2000
Smith J D, Lawson C, Yacoub M H, Rose M L
Abstract excerpt
Chronic graft rejection, characterized by a gradual occlusion of grafted vessels, is the most serious complication following heart and kidney transplantation. Although often associated with chronic production of anti-HLA and anti-endothelial antibodies, the precise role of antibodies in chronic rejection remains uncertain. Here we have investigated whether HLA-specific antibodies, either monoclonal or derived...
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