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Article

Atypical clustering of gynecologic malignancies: A family study including molecular analysis of candidate genes.

Gynecologic oncology - 1 Apr 2000

Cohn D E, Babb S, Whelan A J, Mutch D G, Herzog T J, Rader J S, Elbendary A, Goodfellow P J

Abstract excerpt

OBJECTIVE: We set out to determine whether hereditary nonpolyposis colorectal cancer (HNPCC) was responsible for cancer susceptibility in a family with gynecologic malignancies in three consecutive generations. METHODS: A detailed family history study, including review of medical records, was undertaken. Tumor DNAs from affected family members were evaluated for microsatellite instability (MSI). Linkage between...

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Topics

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Share to Chromosomes, Human, Pair 2
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Neoplasm

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Share to Genital Neoplasms, Female

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Source

Identifiers

PMID: 10739686
DOI: 10.1006/gyno.1999.5709

Genes

MSH2
MLH1
MSH3
MSH6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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