Article
Characterization of polymorphisms in the promoter of the human angiotensin II subtype 1 (AT1) receptor gene.
Annals of human genetics - 1 Jul 1999
Erdmann J, Riedel K, Rohde K, Folgmann I, Wienker T, Fleck E, Regitz-Zagrosek V
Abstract excerpt
In this study eight sequence variants in the functional promoter of the human angiotensin II subtype 1 (AT1 or AGTR1) receptor gene are reported. Six of these variants are in nearly total linkage disequilibrium with each other and occur with a frequency of 15.7%. By haplotype estimation this group of eight sequence variants is characterized by only five haplotypes. There is no linkage disequilibrium between one...
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