Article
Evidence for involvement of the type 1 angiotensin II receptor locus in essential hypertension.
Hypertension (Dallas, Tex. : 1979) - 1 Mar 1999
Kainulainen K, Perola M, Terwilliger J, Kaprio J, Koskenvuo M, Syvänen A C, Vartiainen E, Peltonen L, Kontula K
Abstract excerpt
Components of the renin-angiotensin system play an important role in the normal regulation of blood pressure. We carried out a comprehensive genetic linkage study of the genes involved in the renin-angiotensin cascade in Finnish hypertensive twins and their affected siblings. We found no evidence for linkage between essential hypertension and the genes coding for renin, angiotensinogen, angiotensin-converting...
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