Characterization of polymorphisms at the 11 beta-hydroxylase (CYP11B1) locus.

doi:10.1046/j.1469-1809.1998.6220181.x

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Article

Characterization of polymorphisms at the 11 beta-hydroxylase (CYP11B1) locus.

Annals of human genetics - 1 Mar 1998

Skinner C A, Yousaf N, Honour J W, Rumsby G

Abstract excerpt

Four sequence variants in the 11 beta-hydroxylase (CYP11B1) gene are reported. One of the sequence changes occurs in exon 1 and is in linkage disequilibrium with a second variant in intron 3. The other two changes occur at adjacent nucleotides in intron 1. The finding of easily demonstrable, intr...

Topics

Alleles
DNA Restriction Enzymes
Exons
Gene Frequency
Humans
Introns
Linkage Disequilibrium
Polymorphism, Genetic
Steroid 11-beta-Hydroxylase

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