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Article

The high copper tolerance of Candida albicans is mediated by a P-type ATPase.

Proceedings of the National Academy of Sciences of the United States of America - 28 Mar 2000

Weissman Z, Berdicevsky I, Cavari B Z, Kornitzer D

Abstract excerpt

The pathogenic yeast Candida albicans has higher resistance than the baker's yeast Saccharomyces cerevisiae to elevated concentrations of copper. To understand the basis of this differential resistance, we performed a functional screen for C. albicans genes involved in copper detoxification. Here, we report the isolation of two such genes: a metallothionein, CaCUP1, and a copper-transporting P-type ATPase,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 10737803
DOI: 10.1073/pnas.97.7.3520
PMCID: PMC16272

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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