Article
Detection of infectious HIV in circulating monocytes from patients on prolonged highly active antiretroviral therapy.
Journal of acquired immune deficiency syndromes (1999) - 1 Feb 2000
Lambotte O, Taoufik Y, de Goër M G, Wallon C, Goujard C, Delfraissy J F
Abstract excerpt
The existence of a reservoir of resting CD4+ T cells harboring latent replication-competent HIV has been demonstrated in patients on prolonged highly active antiretroviral therapy (HAART). Latently infected tissue macrophages may constitute a second HIV reservoir. The pool of these cells may be maintained by incoming infected monocytes from blood and/or by in situ viral replication. In this study, the presence of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.