Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Use of recombinant inbred strains for evaluation of intermediate phenotypes in spontaneous hypertension.

Clinical and experimental pharmacology & physiology - 1 Nov 1994

Kunes J, Kren V, Pravenec M, Zicha J

Abstract excerpt

1. The HXB/BXH recombinant inbred (RI) strains, derived from the spontaneously hypertensive rat (SHR) and the normotensive Brown Norway (BN.1x) rat, represent a very useful system for gene mapping and for genetic analysis of certain model diseases, such as spontaneous hypertension. 2. These RI strains were genotyped in multiple genetic polymorphisms and characterized in blood pressure and some intermediate...

Topics

Animals
Disease Models, Animal
Hypertension
Phenotype
Rats
Rats, Inbred BN
Rats, Inbred SHR
Recombination, Genetic

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7882582
DOI: 10.1111/j.1440-1681.1994.tb02463.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7882582-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Use of recombinant inbred strains for evaluation of intermediate phenotypes in spontaneous hypertension.PMID 7882582Read ↗

Invited Review: HXB/BXH rat recombinant inbred strain platform: a newly enhanced tool for cardiovascular, behavioral, and developmental genetics and genomicsSemantic proximity Read ↗

HXB/Ipcv and BXH/Cub recombinant inbred strains of the rat: strain distribution patterns of 632 alleles.Semantic proximity Read ↗

Renal renin activity in recombinant inbred strains is related to abnormal renin gene: the role of blood pressure changes.Semantic proximity Read ↗

Newborn and adult recombinant inbred strains: a tool to search for genetic determinants of target organ damage in hypertension.Semantic proximity Read ↗

A new framework marker-based linkage map and SDPs for the rat HXB/BXH strain set.Semantic proximity Read ↗

Use of AFLP markers for gene mapping and QTL detection in the rat.Semantic proximity Read ↗

Genetic characterization of novel strains of rats derived from crosses between Wistar-Kyoto and spontaneously hypertensive rats, and comparisons with their parental strains.Semantic proximity Read ↗

Genetic models of hypertension in experimental animals.Semantic proximity Read ↗

Cosegregation of blood pressure with a kallikrein gene family polymorphism.Semantic proximity Read ↗

Characterization of new inbred strains of Dahl-Iwai salt-sensitive and salt-resistant rats.Semantic proximity Read ↗

A genetic and correlation analysis of liver cholesterol concentration in rat recombinant inbred strains fed a high cholesterol diet.Semantic proximity Read ↗

Evaluation of LEXF/FXLE rat recombinant inbred strains for genetic dissection of complex traits.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.