Article
Spontaneous apoptosis and highly active antiretroviral therapy (HAART).
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Feb 2000
Dieye T N, Van Vooren J P, Delforge M L, Liesnard C, Devleeschouwer M, Farber C M
Abstract excerpt
Increased programmed cell death (PCD) or apoptosis has been detected in the T cells of HIV-infected subjects; it is held partially responsible for the continuous loss of CD4+ T cells during the natural course of HIV infection. Highly active antiretroviral therapy (HAART) decreases the viral load and leads to an increase of CD4+ count in vivo. In this study we evaluated PCD in total peripheral blood mononuclear...
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