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Article

The role of E-cadherin in low-grade ductal breast tumourigenesis.

The Journal of pathology - 1 May 2003

Roylance Rebecca, Droufakou Stavroula, Gorman Patricia, Gillett Cheryl, Hart Ian R, Hanby Andrew, Tomlinson Ian

Abstract excerpt

Grade I invasive ductal breast carcinomas have a specific pattern of genetic aberrations, namely gain of 1q and loss of 16q. This pattern is very similar to the changes seen in invasive lobular breast carcinomas (ILCs). The gene on 16q involved in ILC is known to be E-cadherin (CDH1). This study has investigated whether the same gene is responsible for grade I invasive ductal carcinoma (IDC), using allele...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12692841
DOI: 10.1002/path.1326

Genes

CDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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