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Article

Cyclin D1 and associated proteins in mammary ductal carcinomain situ and atypical ductal hyperplasia

1 Apr 1998

Abstract excerpt

Experimental studies suggest that cyclin D1 is a potential oncogene but in clinical studies of invasive breast cancer, overexpression of cyclin D1 is found to be associated with oestrogen receptor (ER) expression and low histological grade, both markers of good prognosis. Immunohistochemistry has been used to examine the relationship between cyclin D1 expression and differentiation in 36 cases of ductal carcinoma...

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PMID: 9664905
DOI: 10.1002/(sici)1096-9896(199804)184:4<396::aid-path1259>3.0.co;2-g

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