Article
Hsp90 is a core centrosomal component and is required at different stages of the centrosome cycle in Drosophila and vertebrates.
The EMBO journal - 15 Mar 2000
Lange B M, Bachi A, Wilm M, González C
Abstract excerpt
To determine the molecular composition of the centrosome of a higher eukaryote, we carried out a systematic nano-electrospray tandem or MALDI mass spectrometry analysis of the polypeptides present in highly enriched preparations of immunoisolated Drosophila centrosomes. One of the proteins identified is Hsp83, a member of the highly conserved Hsp90 family including chaperones known to maintain the activity of...
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