Article
Polymorphism in the gelatinase B gene and the severity of coronary arterial stenosis.
Clinical science (London, England : 1979) - 1 Jul 2001
Wang J, Warzecha D, Wilcken D, Wang X L
Abstract excerpt
Gelatinase B, as one of the matrix metalloproteinases, may be relevant to atherogenic plaque development and stability. Recently, a C-1562T substitution in the regulatory region of the gelatinase B gene was shown to up-regulate gelatinase B expression, which could be relevant to both the severity and stability of atherosclerotic plaques. We determined the genotype of 788 angiographically documented Caucasian...
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