Article
Phenotype-dependent expression of cadherin 6B in vascular and visceral smooth muscle cells.
FEBS letters - 3 Mar 2000
Chimori Y, Hayashi K, Kimura K, Nishida W, Funahashi S, Miyata S, Shimane M, Matsuzawa Y, Sobue K
Abstract excerpt
We used mRNA subtraction of differentiated and dedifferentiated smooth muscle cells (SMCs) to reveal the molecular mechanisms underlying the phenotypic modulation of SMCs. With this approach, we found that a 10 kb mRNA encoding a homotypic cell adhesion molecule, cadherin 6B, was strongly expressed in differentiated vascular and visceral SMCs, but not in the dedifferentiated SMCs derived from them. In vivo,...
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