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Article

Mutational analysis of archaeal histone-DNA interactions.

Journal of molecular biology - 17 Mar 2000

Soares D J, Sandman K, Reeve J N

Abstract excerpt

Site-specific mutagenesis of the hmfB gene cloned from the archaeon Methanothermus fervidus, followed by expression in Escherichia coli, has been used to generate approximately 90 recombinant (r) variants of the archaeal histone HMfB. The abilities of these variants to form stable archaeal nucleosome-containing complexes with linear pBR322 DNA, and with an 89 bp restriction fragment of this DNA have been...

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PMID: 10704305
DOI: 10.1006/jmbi.2000.3546

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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