Article
Histone variants in archaea and the evolution of combinatorial chromatin complexity.
Proceedings of the National Academy of Sciences of the United States of America - 29 Dec 2020
Stevens Kathryn M, Swadling Jacob B, Hocher Antoine, Bang Corinna, Gribaldo Simonetta, Schmitz Ruth A, Warnecke Tobias
Abstract excerpt
Nucleosomes in eukaryotes act as platforms for the dynamic integration of epigenetic information. Posttranslational modifications are reversibly added or removed and core histones exchanged for paralogous variants, in concert with changing demands on transcription and genome accessibility. Histones are also common in archaea. Their role in genome regulation, however, and the capacity of individual paralogs to...
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