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Free mycolic acid accumulation in the cell wall of the mce1 operon mutant strain of Mycobacterium tuberculosis.

Journal of microbiology (Seoul, Korea) - 1 Oct 2013

Cantrell Sally A, Leavell Michael D, Marjanovic Olivera, Iavarone Anthony T, Leary Julie A, Riley Lee W

Abstract excerpt

The lipid-rich cell wall of Mycobacterium tuberculosis, the agent of tuberculosis, serves as an effective barrier against many chemotherapeutic agents and toxic host cell effector molecules, and it may contribute to the mechanism of persistence. Mycobacterium tuberculosis strains mutated in a 13-gene operon called mce1, which encodes a putative ABC lipid transporter, induce aberrant granulomatous response in...

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PMID: 24037657
DOI: 10.1007/s12275-013-3092-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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