Article
Post-translational modifications of immunoglobulin G: a mouse IgG variant that lacks the entire CH1 domain.
Molecular immunology - 1 Jan 2000
Masuda K, Yamaguchi Y, Kato K, Kim H H, Takahashi N, Shimada I, Arata Y
Abstract excerpt
In the present study, we characterized the post-translational modifications of a short-chain variant of mouse IgG2a that lacks the entire CH 1 domain. The short-chain IgG2a and its proteolytic fragments were subjected to electrospray ionization- and fast atom bombardment-mass spectrometric analyses. It has been demonstrated that approximately 14% of the heavy chain of the short-chain IgG2a is O-glycosylated with...
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