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Article

Expression of mRNA and protein of nucleoproteins during human spermiogenesis

1 Oct 1998

Abstract excerpt

The most important event determining the nuclear status of sperm cells is the replacement of histones by protamines, which are the basic nuclear proteins of mature spermatozoa. A first step in this exchange is the displacement of histones by transition proteins (TP). Our study demonstrates, for the first time, the sequential expression of the testis-specific histone (H1t) and the transition proteins (TP1 and TP2)...

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PMID: 9809674
DOI: 10.1093/molehr/4.10.939

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