Article
Functions of thyroid hormone receptors in mice.
Thyroid : official journal of the American Thyroid Association - 1 Jan 2000
Forrest D, Vennström B
Abstract excerpt
Thyroid hormone receptors (TRs) play a central role in mediating the actions of thyroid hormone in development and homeostasis in vertebrate species. The TRs are nuclear receptors that act as ligand-regulated transcription factors. There are two TR genes (TRalpha and TRbeta), each capable of generating different variant products, suggesting a potentially complex array of TR pathways. Targeted mutagenesis in the...
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