Article
[The value of pharmacogenetic tests in antidepressive medication therapy].
Der Nervenarzt - 1 Nov 2005
Kirchheiner J, Sasse J, Roots I, Brockmöller J, Bauer M
Abstract excerpt
The pharmacokinetics and effect of antidepressants are influenced by genetic factors. Modern methods of genotyping allow fast and inexpensive identification of genetic variants and thus can be used in clinical diagnostics to improve the tolerance to drug therapy. Numerous studies have investigated the significance of genetic variants in drug-metabolizing enzymes, drug and natural substrate transporters,...
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