Article
Pharmacogenetics and antipsychotics in the light of personalized pharmacotherapy.
Psychiatria Danubina - 1 Jun 2010
Mihaljević-Peles Alma, Sagud Marina, Bozina Nada, Zivković Maja, Jovanović Nikolina
Abstract excerpt
The concept of personalized drug therapy on the basis of genetic investigations has become a major issue in psychopharmacology. Pharmacogenetic studies have focused on polymorphisms in liver cytochrome P450 isoenzymes that metabolize many antidepressant and antipsychotic medications. The most significant results are the association between drug metabolic polymorphisms of cytochrome P450 with variations in drug...
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