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Article

Design of experiments for fine-mapping quantitative trait loci in livestock populations.

BMC genetics - 29 Jun 2020

Wittenburg Dörte, Bonk Sarah, Doschoris Michael, Reyer Henry

Abstract excerpt

BACKGROUND: Single nucleotide polymorphisms (SNPs) which capture a significant impact on a trait can be identified with genome-wide association studies. High linkage disequilibrium (LD) among SNPs makes it difficult to identify causative variants correctly. Thus, often target regions instead of single SNPs are reported. Sample size has not only a crucial impact on the precision of parameter estimates, it also...

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Identifiers

PMID: 32600319
DOI: 10.1186/s12863-020-00871-1
PMCID: PMC7324978

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