Article
Selection and genetic drift of polymorphisms within the merozoite surface protein-1 gene of Plasmodium falciparum.
Gene - 11 Jan 2000
Tanabe K, Sakihama N, Nakamura Y, Kaneko O, Kimura M, Ferreira M U, Hirayama K
Abstract excerpt
Intragenic recombination in the merozoite surface protein-1 gene (Msp-1) of Plasmodium falciparum is a major mechanism for allelic variation among natural parasite populations. The frequency of recombination depends on the intensity of transmission in the vector mosquito. In the present study, linkage disequilibrium between polymorphic 'loci' in the 5'- and 3'-regions of Msp-1 was examined in parasite populations...
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