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VOLIN and KJON—Two novel hyperdiploid myeloma cell lines

17 Jun 2016

Abstract excerpt

Multiple myeloma can be divided into two distinct genetic subgroups: hyperdiploid (HRD) or nonhyperdiploid (NHRD) myeloma. Myeloma cell lines are important tools to study myeloma cell biology and are commonly used for preclinical screening and testing of new drugs. With few exceptions human myeloma cell lines are derived from NHRD patients, even though about half of the patients have HRD myeloma. Thus, there is a...

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PMID: 27311012
DOI: 10.1002/gcc.22388

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