Molecular analysis of genes encoding outer surface protein C (OspC) of Borrelia burgdorferi sensu lato: relationship to ospA genotype and evidence of lateral gene exchange of ospC.

doi:10.1128/jcm.33.7.1860-1866.1995

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Article

Molecular analysis of genes encoding outer surface protein C (OspC) of Borrelia burgdorferi sensu lato: relationship to ospA genotype and evidence of lateral gene exchange of ospC.

Journal of clinical microbiology - 1 Jul 1995

Jauris-Heipke S, Liegl G, Preac-Mursic V, Rössler D, Schwab E, Soutschek E, Will G, Wilske B

Abstract excerpt

It has been shown by analysis with monoclonal and polyclonal antibodies that outer surface protein C (OspC) of Borrelia burgdorferi sensu lato is highly heterogeneous. To determine if the heterogeneity has a genetic basis, the genes of 18 different B. burgdorferi sensu lato strains have been ampl...

Topics

Amino Acid Sequence
Animals
Antigens, Bacterial
Antigens, Surface
Bacterial Outer Membrane Proteins
Bacterial Vaccines
Borrelia
Borrelia burgdorferi Group
Cloning, Molecular
Cluster Analysis
Consensus Sequence
Genes, Bacterial
Genetic Variation

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genotype

Humans

Lipoproteins

Molecular Sequence Data

Recombination, Genetic

Source

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Identifiers

PMID: 7665660
DOI: 10.1128/jcm.33.7.1860-1866.1995
PMCID: PMC228286

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7665660-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.