Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cost-effectiveness of preventive strategies for women with a BRCA1 or a BRCA2 mutation.

Annals of internal medicine - 21 Mar 2006

Anderson Kristin, Jacobson Judith S, Heitjan Daniel F, Zivin Joshua Graff, Hershman Dawn, Neugut Alfred I, Grann Victor R

Abstract excerpt

BACKGROUND: For BRCA1 or BRCA2 mutation carriers, decision analysis indicates that prophylactic surgery or chemoprevention leads to better survival than surveillance alone. OBJECTIVE: To evaluate the cost-effectiveness of the preventive strategies that are available to unaffected women carrying a single BRCA1 or BRCA2 mutation with high cancer penetrance. DESIGN: Markov modeling with Monte Carlo simulations and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Markov Chains
Share to Cost-Benefit Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, BRCA1

Share to Genes, BRCA2

Share to Mastectomy

Share to Monte Carlo Method

Share to Ovarian Neoplasms

Share to Ovariectomy

Source

Identifiers

PMID: 16549852
DOI: 10.7326/0003-4819-144-6-200603210-00006

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cost-effectiveness of preventive strategies for women with a BRCA1 or a BRCA2 mutation.PMID 16549852Read ↗

Comparative effectiveness of screening and prevention strategies among BRCA1/2-affected mutation carriers.Semantic proximity Read ↗

Cost-effectiveness of different strategies to prevent breast and ovarian cancer in German women with a BRCA 1 or 2 mutation.Semantic proximity Read ↗

Prevention with tamoxifen or other hormones versus prophylactic surgery in BRCA1/2-positive women: a decision analysis.Semantic proximity Read ↗

Effect of prevention strategies on survival and quality-adjusted survival of women with BRCA1/2 mutations: an updated decision analysis.Semantic proximity Read ↗

Decision-analytic evaluation of the comparative effectiveness and cost-effectiveness of strategies to prevent breast and ovarian cancer in German women with BRCA-1/2 mutations.Semantic proximity Read ↗

Decision analysis of prophylactic mastectomy and oophorectomy in BRCA1-positive or BRCA2-positive patients.Semantic proximity Read ↗

Survival analysis of cancer risk reduction strategies for BRCA1/2 mutation carriers.Semantic proximity Read ↗

A MDP model for breast and ovarian cancer intervention strategies for BRCA1/2 mutation carriers.Semantic proximity Read ↗

Cost-effectiveness of testing for breast cancer susceptibility genes.Semantic proximity Read ↗

Life expectancy gains from cancer prevention strategies for women with breast cancer and BRCA1 or BRCA2 mutations.Semantic proximity Read ↗

Testing for the BRCA1 and BRCA2 breast-ovarian cancer susceptibility genes: a decision analysis.Semantic proximity Read ↗

Decision analysis of prophylactic surgery or screening for BRCA1 mutation carriers: a more prominent role for oophorectomy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.