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Molecular Evolution of Marek's Disease Virus (MDV) Field Strains in a 40-Year Time Period

1 Dec 2014

Abstract excerpt

Marek's disease (MD) presents a serious threat in poultry production. The disease has been limited for over 40 yr by protective vaccination. The widely applied vaccination against MD is also one of the factors causing evolutionary pressure onto field Marek's disease virus (MDV) virulent strains. Molecular evolution of MDV genes involved in oncogenesis may increase the pathogenicity of MDV virulent strains. The...

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PMID: 25618999
DOI: 10.1637/10812-030614-reg.1

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