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Article

Involvement of Tcf/Lef in establishing cell types along the animal-vegetal axis of sea urchins.

Development genes and evolution - 1 Feb 2000

Huang L, Li X, El-Hodiri H M, Dayal S, Wikramanayake A H, Klein W H

Abstract excerpt

Members of the Tcf/Lef family interact with beta-catenin to activate programs of gene expression during development. Recently beta-catenin was shown to be essential for establishing cell fate along the animal-vegetal axis of the sea urchin embryo. To examine the role of Tcf/Lef in sea urchins we cloned a Strongylocentrotus purpuratus Tcf/Lef homolog. Expression of SpTcf/Lef was maximal when beta-catenin became...

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PMID: 10664150
DOI: 10.1007/s004270050013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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