Article
Disruption of the 3' phosphoglycerate kinase (pgk) gene in Aspergillus nidulans.
Current genetics - 1 Feb 1993
Streatfield S J, Roberts C F
Abstract excerpt
We report the isolation of a pgk- mutant strain of Aspergillus nidulans by means of a gene disruption strategy, and demonstrate that the pgk gene is located on chromosome VIII. The pgk- mutant conidiates poorly, will only grow on media supplemented with both a glycolytic and a gluconeogenic carbon source, and is inhibited by hexoses.
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