Article
Developmental disease and cancer: biological and clinical overlaps.
American journal of medical genetics. Part A - 1 Nov 2013
Bellacosa Alfonso
Abstract excerpt
Numerous parallelisms exist between development and cancer. In this article, I review some of the founding ideas linking development and cancer, and highlight clinical conditions exhibiting features of both developmental derangement and cancer predisposition, including cohesinopathies, rasopathies, phakomatoses, Proteus syndrome and other overgrowth disorders, recessive chromosome breakage syndromes, and dominant...
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