Article
[Hereditary tumor syndrome: of its concept and classification].
Nihon rinsho. Japanese journal of clinical medicine - 1 Jun 2000
Baba S
Abstract excerpt
With the cloning of cancer-predisposing genes many responsible genes have been identified from hereditary tumor syndrome over the past 10 years. Cancer is a genetic disease, arising from accumulation of mutations that promote clonal selection of cells and tumor progression. An individual who carries a mutant allele of an inherited cancer gene has a variable cancer risk. The proteins encoded by inherited cancer...
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