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Article

Cloning and Characterization of the Bovine MHC Class I-Like Fc Receptor,

1 Feb 2000

Abstract excerpt

In the cow, maternal immunity is exclusively mediated by colostral Igs, but the receptor responsible for the IgG transport has not yet been identified. The role of an IgG-Fc receptor (FcRn) that resembles a class I MHC Ag in transporting IgGs through epithelial cells was recently shown in selected species. We now report the cloning and characterization of the bovine FcRn (bFcRn). The cDNA and deduced amino acid...

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PMID: 10657638
DOI: 10.4049/jimmunol.164.4.1889

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