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Article

Three-dimensional reconstruction of thin filaments containing mutant tropomyosin.

Biophysical journal - 1 Feb 2000

Rosol M, Lehman W, Craig R, Landis C, Butters C, Tobacman L S

Abstract excerpt

Interactions of the components of reconstituted thin filaments were investigated using a tropomyosin internal deletion mutant, D234, in which actin-binding pseudo-repeats 2, 3, and 4 are missing. D234 retains regions of tropomyosin that bind troponin and form end-to-end tropomyosin bonds, but has a length to span only four instead of seven actin monomers. It inhibits acto-myosin subfragment 1 ATPase (acto-S-1...

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Identifiers

PMID: 10653803
DOI: 10.1016/S0006-3495(00)76648-3
PMCID: PMC1300693

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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