Full-thickness skin grafts from flaky skin mice to nude mice: maintenance of the psoriasiform phenotype.

doi:10.1111/1523-1747.ep12377741

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Article

Full-thickness skin grafts from flaky skin mice to nude mice: maintenance of the psoriasiform phenotype.

The Journal of investigative dermatology - 1 May 1994

Sundberg J P, Dunstan R W, Roop D R, Beamer W G

Abstract excerpt

Flaky skin (fsn) is an autosomal recessive mouse mutation with papulosquamous disease features similar to human psoriasis. In fsn/fsn skin, one sees marked acanthosis and hyperkeratosis with focal parakeratosis, subcorneal pustules, dermal capillary dilation, and a marked diffuse dermal infiltrat...

Topics

Animals
Cell Survival
Epidermis
Female
Genotype
Immunohistochemistry
Kinetics
Male
Mice
Mice, Mutant Strains
Mice, Nude
Phenotype
Psoriasis
Skin Transplantation
Thymidine
Tritium

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