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Article

p21WAF1 regulates anchorage-independent growth of HCT116 colon carcinoma cells via E-cadherin expression.

Cancer research - 1 Jan 2000

Mueller S, Cadenas E, Schönthal A H

Abstract excerpt

The cyclin-dependent kinase inhibitor p21WAF1 has been characterized as an important effector of the tumor suppressor p53 and has been linked to various growth-regulatory processes. To identify a potential role of p21 in anchorage-dependent growth control, we analyzed a pair of HCT116 human colon carcinoma cell lines that differed only in their p21 status. We found that during suspension culture, HCT116 cells...

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PMID: 10646868

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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p21WAF1 regulates anchorage-independent growth of HCT116 colon carcinoma cells via E-cadherin expression.PMID 10646868Read ↗

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