Article
B-lymphoblastoid cell lines as a source of reference DNA for human platelet and neutrophil antigen genotyping.
Transfusion - 1 Jan 2000
Carl B, Kroll H, Bux J, Bein G, Santoso S
Abstract excerpt
BACKGROUND: Human platelet and neutrophil antigens (HPAs, HNAs) are targets for platelet or granulocyte antibodies causing immune thrombocytopenia or neutropenia, respectively. Currently, genotyping is replacing phenotyping as the preferred method of diagnosis of immune cytopenia. To establish a reliable genotyping analysis, however, the availability as reference DNA of genomic DNA from persons of known genotype...
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