Cell line DNA typing in forensic genetics--the necessity of reliable standards.

doi:10.1016/j.forsciint.2003.09.002

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Article

Cell line DNA typing in forensic genetics--the necessity of reliable standards.

Forensic science international - 17 Dec 2003

Szibor Reinhard, Edelmann Jeanett, Hering Sandra, Plate Ines, Wittig Holger, Roewer Lutz, Wiegand Peter, Calì Francesco, Romano Valentino, Michael Matthias

Abstract excerpt

The incorporation of reference DNA is crucial to the validation of any DNA typing protocol. This paper aims to provide a panel of reference DNAs for actual forensic profiling strategies, i.e. autosomal and gonosomal STR typing as well as mtDNA sequencing. We have characterised three human lymphoid cell lines, GM9947, GM9948 and GM3657, and considered 58 autosomal and gonosomal microsatellites as well as the...

Topics

Cell Line, Tumor
DNA Fingerprinting
DNA Primers
DNA, Mitochondrial
Female
Genotype
Humans
K562 Cells
Male
Quality Control
Reference Standards
Tandem Repeat Sequences

Source

Open in PubMed

Identifiers

PMID: 14642717
DOI: 10.1016/j.forsciint.2003.09.002

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