Article
Analysis of fas ligand gene mutation in patients with systemic lupus erythematosus.
Arthritis and rheumatism - 1 Jan 2000
Kojima T, Horiuchi T, Nishizaka H, Sawabe T, Higuchi M, Harashima S I, Yoshizawa S, Tsukamoto H, Nagasawa K, Niho Y
Abstract excerpt
OBJECTIVE: To investigate the possible association of a Fas ligand (FasL) gene mutation(s) or polymorphism(s) with systemic lupus erythematosus (SLE). METHODS: For amplification of the introns of the FasL gene, long polymerase chain reaction (PCR) using exon-based primers was utilized, followed by partial sequencing to construct exon-specific oligonucleotide primers for the analyses of FasL genomic DNA in SLE...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.