Article
Preferential type 1-1 cytokine gene expressions in peripheral T-cell lymphomas.
Hematological oncology - 1 Sept 1999
Ho J W, Liang R H, Srivastava G
Abstract excerpt
In this study, we have investigated whether a pattern of cytokine gene expression can be found in non-Hodgkin's peripheral T-cell lymphoma (PTCL). By using RNase protection assays and RT-PCR, we have systematically studied IL1alpha, IL1beta, IL1-Ra, IL2, IL4, IL5, IL6, IL9, IL10, IL12p35, IL12p40, IL13, IL14, IL15, IFNgamma, IFNbeta, TNFalpha, TNFbeta, LTbeta, and TGFbeta1, TGFbeta2 and TGFbeta3. Twenty-two cases...
Topics
- Cytokines
- Gene Expression Regulation, Neoplastic
- Humans
- Interferons
- Interleukins
- Killer Cells, Natural
- Lymphocyte Subsets
- Lymphoma, T-Cell, Peripheral
- Phenotype
- Reverse Transcriptase Polymerase Chain Reaction
- T-Lymphocytes
- Tumor Necrosis Factor-alpha
