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Article

Cytokine expression by head and neck squamous cell carcinomas.

American journal of surgery - 1 Dec 1992

Mann E A, Spiro J D, Chen L L, Kreutzer D L

Abstract excerpt

Cytokines are known to play an important role in host defense by regulating the function, growth, and differentiation of the cells of the immune system. We hypothesize that, in the tumor microenvironment, tumor cells and resident tissue cells (e.g., fibroblasts) also produce cytokines that may regulate the local immune response to tumors. Initially, homogenates of eight head and neck squamous cell carcinomas...

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Identifiers

PMID: 1463101
DOI: 10.1016/s0002-9610(05)80708-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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