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Article

Dominant Infiltration of TH 1-type CD4 <sup>+</sup> T Cells at the Retrobulbar Space of Patients with Thyroid-Associated Ophthalmopathy

1 Mar 1999

Abstract excerpt

Lymphocyte infiltration in the retrobulbar space is a prominent histological feature of thyroid-associated ophthalmopathy (TAO). We have characterized phenotypic and functional features of T cells derived from retrobulbar infiltrates of 3 TAO patients to better understand their roles in the disease. One hundred four T-cell clones (TCC) were directly established from cells of retrobulbar tissues using a highly...

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PMID: 10211609
DOI: 10.1089/thy.1999.9.305

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