Article
Associations between the leptin receptor gene and adiposity in middle-aged Caucasian males from the HERITAGE family study.
The Journal of clinical endocrinology and metabolism - 1 Jan 2000
Chagnon Y C, Wilmore J H, Borecki I B, Gagnon J, Pérusse L, Chagnon M, Collier G R, Leon A S, Skinner J S, Rao D C, Bouchard C
Abstract excerpt
Linkage and association studies between three exonic polymorphisms in the leptin receptor gene and body composition variables in the HERITAGE Family Study were undertaken. Polymorphisms K109R, Q223R, and K656N have been analyzed with body mass index (BMI), sum of height skinfolds (SF8), fat mass (FM), percent body fat (%FAT), fat free mass, and plasma leptin level. Single-point linkage analysis and covariance...
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